Document Type

Article

Department/Program

Chemistry

Pub Date

2016

Place of Publication

52

Volume

52

Issue

1

First Page

88

Abstract

The importance of bioconjugates within the field of chemistry drives the need for novelmethodologies for their preparation. Well-defined and stable bioconjugates are easily accessible via the utilization of unnatural amino acids (UAAs). As such, we have synthesized and incorporated two new UAAs into green fluorescent protein, and optimized a novel Cadiot-Chodkiewicz bioconjugation, effectively expanding the toolbox of chemical reactions that can be employed in the preparation of bioconjugates.

DOI

10.1039/c5cc08287k

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