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Modeling the Effects of Genetic Manipulations of Calsequestrin on Local Calcium Release and Depletion in Cardiac Myocytes
Carpenter, Ryan P. ; Smith, Gregory D. ; Gyorke, Sandor
Carpenter, Ryan P.
Smith, Gregory D.
Gyorke, Sandor
Abstract
"Cardiac calsequestrin (CASQ2), a Ca buffer localized to the junctional SR (jSR) of cardiac myocytes, is known to bind to the RyR-triadin-junctin complex, participate in the luminal regulation of RyRs, and modulate Ca spark activity..."
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2010-01-01
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Applied Science
DOI
https://doi.org/10.1016/j.bpj.2009.12.581
