Loading...
Gender-Specific Neuromuscular Adaptations to Unloading in Isolated Rat Soleus Muscles
Deschenes, Michael R. Leathrum, Colleen M. Deschenes, Michael R.
Deschenes, Michael R.
Leathrum, Colleen M.
Deschenes, Michael R.
Abstract
Introduction: The potential of gender to affect unloading-induced neuromuscular adaptations was investigated. Methods: Twenty male and 20 female rats were assigned to control (CTL), or unloaded (UL) conditions. After 2 weeks of unloading, soleus muscles were removed, and neuromuscular function was assessed during a train of alternating indirect (neural) and direct (muscle) stimuli. Results: In rested muscle, strength showed significant (P female) and treatment (CTL > UL). By the end of the testing protocol, when muscles showed fatigue, gender-related and treatment-related differences in strength had disappeared. Neuromuscular transmission efficiency and strength suffered a greater decline during the testing protocol in males than females. Unloaded male muscles displayed greater contractile velocity than female muscles both when rested and fatigued. Conclusions: Gender affected unloading-induced neuromuscular adaptations. The greater strength of rested male muscles was due to greater muscle mass and neuromuscular transmission efficiency.
Description
Date
2016-01-01
Journal Title
Journal ISSN
Volume Title
Publisher
Collections
Download Dataset
Files
Loading...
gender_specific.pdf
Adobe PDF, 422.49 KB
Rights Holder
Usage License
Embargo
Research Projects
Organizational Units
Journal Issue
Keywords
Citation
Advisor
Department
Kinesiology & Health Sciences
DOI
10.1002/mus.25038