Date Thesis Awarded

5-2021

Access Type

Honors Thesis -- Access Restricted On-Campus Only

Degree Name

Bachelors of Science (BS)

Department

Chemistry

Advisor

Jonathan Scheerer

Committee Members

Elizabeth Harbron

Mark Forsyth

Abstract

This thesis details a novel method for the construction of substituted pyridines using oxazinones in a cycloaddition/cycloreversion tandem sequence. A novel route to the oxazinone precursor is reported, and the reaction scope is explored through reactions with various alkynes. An application of the chemistry to the synthesis of a selective ErbB4 receptor inhibitor is described.

Available for download on Friday, May 12, 2023

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