Loading...
1,4-Oxazinones as Intermediates in the Construction of Complex Pyridine Products
Thompson, Lynleigh C
Thompson, Lynleigh C
Abstract
This thesis describes the construction of complex pyridine products using 1,4-oxazinones as intermediates. The syntheses of polysubstituted pyridines, 2-azaanthraquinones, and natrual product xylanigripone A are reported through the use of a tandem [4+2]/r[4+2] cycloaddition/cycloreversion sequence using 1,4-oxazinones. In addition, two new methods for the construction of 1,4-oxazinones are presented utilizing safe and inexpensive starting materials, providing novel methods to access substrates in the oxazinone family. This work serves to provide new methods to access biologically relevant products and demonstrates the utility of 1,4-oxazinones as versatile intermediates in the construction of pyridine products.
Description
Date
2025-04-01
Journal Title
Journal ISSN
Volume Title
Publisher
Collections
Download Dataset
Rights Holder
Usage License
Embargo
2027-04-28
Research Projects
Organizational Units
Journal Issue
Keywords
Citation
Department
Chemistry