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Effect of Unloading on Myofiber Profiles in Male and Female Rats

Ramsey, Hailey
Abstract
Many injuries and surgeries result in necessary muscle unloading to aid in recovery. It is known that muscle unloading can lead to muscle atrophy1. A previous study conducted in this lab found that females suffer greater decline in strength than males, as a result of unloading1. Another experiment confirmed that females are more susceptible to adaptations due to unloading and suggested that this is caused by the neural drive from the central nervous system2. This study aims to explain what causes the gender-related discrepancy in strength after unloading by looking at the effect of unloading on the myofiber profiles of male and female rats. The knowledge generated from this experiment can be used to aid in the recovery process from injuries and surgeries that require unloading for recovery.
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2017-02-24
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