Document Type

Article

Department/Program

Chemistry

Journal Title

Molbank

Pub Date

6-29-2009

Volume

2009

Issue

3

Journal Article URL

https://www.mdpi.com/1422-8599/2009/3/M602

First Page

1

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Abstract

The preparation of 5-bromo-2-naphthol (4) in three steps from 5-amino-2-naphthol (1) is described. A sulfonic acid group is introduced at the 1-position as an activating and protecting group for the Sandmeyer reaction. The sulfonate group allows for the use of only water and sulfuric acid as solvents. The sulfonic acid is introduced with three equivalents of sulfuric acid, and it is removed in 20% aq. sulfuric acid.

DOI

10.3390/M602

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Chemistry Commons

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