Document Type
Article
Department/Program
Chemistry
Journal Title
Chemical Communications
Pub Date
2016
Volume
52
Issue
1
First Page
88
Abstract
The importance of bioconjugates within the field of chemistry drives the need for novelmethodologies for their preparation. Well-defined and stable bioconjugates are easily accessible via the utilization of unnatural amino acids (UAAs). As such, we have synthesized and incorporated two new UAAs into green fluorescent protein, and optimized a novel Cadiot-Chodkiewicz bioconjugation, effectively expanding the toolbox of chemical reactions that can be employed in the preparation of bioconjugates.
Recommended Citation
Maza, Johnathan C.; Nimmo, Zachary M.; and Young, Douglas D., Expanding the scope of alkyne-mediated bioconjugations utilizing unnatural amino acids (2016). Chemical Communications, 52(1), 88-91.
10.1039/c5cc08287k
DOI
10.1039/c5cc08287k
