Modeling the Effects of Genetic Manipulations of Calsequestrin on Local Calcium Release and Depletion in Cardiac Myocytes

Authors

Ryan P. Carpenter
Gregory D. Smith, William & MaryFollow
Sandor Gyorke

Document Type

Article

Department/Program

Applied Science

Journal Title

Biophysical Journal

Pub Date

1-2010

Volume

98

Issue

3, Supplement 1

First Page

104A

Abstract

"Cardiac calsequestrin (CASQ2), a Ca buffer localized to the junctional SR (jSR) of cardiac myocytes, is known to bind to the RyR-triadin-junctin complex, participate in the luminal regulation of RyRs, and modulate Ca spark activity..."

Recommended Citation

Carpenter, Ryan P.; Smith, Gregory D.; and Gyorke, Sandor, Modeling the Effects of Genetic Manipulations of Calsequestrin on Local Calcium Release and Depletion in Cardiac Myocytes (2010). Biophysical Journal, 98(3, Supplement 1), 104A-104A.
https://doi.org/10.1016/j.bpj.2009.12.581

DOI

https://doi.org/10.1016/j.bpj.2009.12.581