Document Type

Article

Department/Program

Biology

Journal Title

Caenorhabditis Elegans: Molecular Genetics and Development, Second Edition

Pub Date

2011

Volume

106

First Page

343

Abstract

Although the general events surrounding fertilization in many species are well described, the molecular underpinnings of fertilization are still poorly understood. Caenorhabditis elegans has emerged as a powerful model system for addressing the molecular and cell biological mechanism of fertilization. A primary advantage is the ability to isolate and propagate mutants that effect gametes and no other cells. This chapter provides conceptual guidelines for the identification, maintenance, and experimental approaches for the study fertility mutants.

DOI

10.1016/B978-0-12-544172-8.00013-X

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