Document Type
Article
Department/Program
Applied Science
Journal Title
Annual Review of Physiology, Vol 75
Pub Date
2013
Volume
75
First Page
423
Abstract
Breathing is an essential behavior that presents a unique opportunity to understand how the nervous system functions normally, how it balances inherent robustness with a highly regulated lability, how it adapts to both rapidly and slowly changing conditions, and how particular dysfunctions result in disease. We focus on recent advancements related to two essential sites for respiratory rhythmogenesis: (a) the preBotzinger Complex (preBotC) as the site for the generation of inspiratory rhythm and (b) the retrotrapezoid nucleus/parafacial respiratory group (RTN/pFRG) as the site for the generation of active expiration.
Recommended Citation
Feldman, Jack L.; Del Negro, Christopher A.; and Gray, Paul A., Understanding the Rhythm of Breathing: So Near, Yet So Far (2013). Annual Review of Physiology, Vol 75, 75, 423-452.
10.1146/annurev-physiol-040510-130049
DOI
10.1146/annurev-physiol-040510-130049
