Document Type
Article
Department/Program
Chemistry
Journal Title
SYNLETT
Pub Date
7-2017
Volume
28
Issue
10
Abstract
A domino reaction sequence has been evaluated that begins with union of novel dihydrooxazinone precursors with 2-alkynyl-substituted benzaldehyde components through aldol condensation. Ensuing operations, including alkene isomerization, Diels-Alder, and retrograde Diels-Alder with loss of CO2 occurs in the same reaction vessel to provide polysubstituted tricyclic pyridine products.
Recommended Citation
Williamson, Jill B.; Smith, Emily R.; and Scheerer, Jonathan R., A Merged Aldol Condensation, Alkene Isomerization, Cycloaddition/Cycloreversion Sequence Employing Oxazinone Intermediates for the Synthesis of Substituted Pyridines (2017). SYNLETT, 28(10).
10.1055/s-0036-1588729
DOI
10.1055/s-0036-1588729
