Title
Photo-Controlled Release of Zinc Ions in Aqueous Solution with Simultaneous Fluorescence Detection
Date Thesis Awarded
4-2018
Access Type
Honors Thesis -- Access Restricted On-Campus Only
Degree Name
Bachelors of Science (BS)
Department
Chemistry
Advisor
Elizabeth J. Harbron
Committee Members
Christopher J. Abelt
Nathanael M. Kidwell
Alexander B. Angelov
Abstract
We created a system consisting of a highly fluorescent conjugated polymer nanoparticle paired with a photo-release dye. Upon irradiation at the maximum absorbance of the nanoparticle, it non-radiatively transfers its energy to the dye through the process of FRET (Fluorescence Resonance Energy Transfer), exciting the dye, which then releases a biologically relevant ion, zinc. This system enhances the photo-release process, making it kinetically faster and more efficient. The photo-event is accompanied by a change in fluorescence of the dye, allowing for simultaneous detection of photo-release. This thesis outlines nanoparticle synthesis using the reprecipitation method, synthesis of the zinc releasing dye, and nanoparticle doping procedure.
Recommended Citation
Larson, Tyler, "Photo-Controlled Release of Zinc Ions in Aqueous Solution with Simultaneous Fluorescence Detection" (2018). Undergraduate Honors Theses. William & Mary. Paper 1240.
https://scholarworks.wm.edu/honorstheses/1240
