Title
Photo-Controlled Release of Zinc Ions in Aqueous Solution with Simultaneous Fluorescence Detection
Date Thesis Awarded
4-2018
Document Type
Honors Thesis
Degree Name
Bachelors of Science (BS)
Department
Chemistry
Advisor
Elizabeth J. Harbron
Committee Members
Christopher J. Abelt
Nathanael M. Kidwell
Alexander B. Angelov
Abstract
We created a system consisting of a highly fluorescent conjugated polymer nanoparticle paired with a photo-release dye. Upon irradiation at the maximum absorbance of the nanoparticle, it non-radiatively transfers its energy to the dye through the process of FRET (Fluorescence Resonance Energy Transfer), exciting the dye, which then releases a biologically relevant ion, zinc. This system enhances the photo-release process, making it kinetically faster and more efficient. The photo-event is accompanied by a change in fluorescence of the dye, allowing for simultaneous detection of photo-release. This thesis outlines nanoparticle synthesis using the reprecipitation method, synthesis of the zinc releasing dye, and nanoparticle doping procedure.
Recommended Citation
Larson, Tyler, "Photo-Controlled Release of Zinc Ions in Aqueous Solution with Simultaneous Fluorescence Detection" (2018). Undergraduate Honors Theses. Paper 1240.
https://scholarworks.wm.edu/honorstheses/1240
