Date Thesis Awarded


Access Type

Honors Thesis -- Access Restricted On-Campus Only

Degree Name

Bachelors of Science (BS)




Jonathan Scheerer

Committee Members

Harmony Dalgleish

Elizabeth Harbron

Robert Hinkle


This thesis outlines progress towards the synthesis of aristopyridinone A. Aristopyridinone A is a compound isolated from the traditional Chinese medicine plant Aristolochia manshuriensis. While the plant has been used in a variety of medicinal capacities, the biological activity of aristopyridinone A is unknown. The synthetic pathways presented in this thesis expand on previous work using a merged Diels Alder [4+2] cycloaddition and cycloreversion strategy to form the 2-pyridone core of the aristopyridinone A molecule. These studies also explore the chemistry of the inter-molecular Diels-Alder reaction using a diketopiperazine-derived azadiene.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

On-Campus Access Only