Date Thesis Awarded


Document Type

Honors Thesis

Degree Name

Bachelors of Science (BS)




Jonathan Scheerer

Committee Members

Harmony Dalgleish

Elizabeth Harbron

Robert Hinkle


This thesis outlines progress towards the synthesis of aristopyridinone A. Aristopyridinone A is a compound isolated from the traditional Chinese medicine plant Aristolochia manshuriensis. While the plant has been used in a variety of medicinal capacities, the biological activity of aristopyridinone A is unknown. The synthetic pathways presented in this thesis expand on previous work using a merged Diels Alder [4+2] cycloaddition and cycloreversion strategy to form the 2-pyridone core of the aristopyridinone A molecule. These studies also explore the chemistry of the inter-molecular Diels-Alder reaction using a diketopiperazine-derived azadiene.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.