Date Thesis Awarded

2013

Access Type

Honors Thesis -- Open Access

Degree Name

Bachelors of Science (BS)

Department

Chemistry

Advisor

Jonathan Scheerer

Committee Members

Robert J. Hinkle

Kurt E. Williamson

Abstract

Outlined in this paper is a series of work done towards the construction of bicyclo[2.2.2]diazaoctane structures found in a several natural products. Detailed work is shown for a general method of creating these cores by a domino sequence to rapidly generate these cores with enantio- and diastereoselectivity. A similar sequence this outlined and displayed in the formal synthesis of brevianamide B. This synthesis makes use of a similar domino sequence, but a new source of facial selectivity is used.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

Comments

Thesis is part of Honors ETD pilot project, 2008-2013. Migrated from Dspace in 2016.

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Chemistry Commons

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