Radiotherapy and Oncology
Journal Article URL
Glioblastoma multiforme (GBM) represents the most common and deadly primary brain malignancy, particularly due to temozolomide (TMZ) and radiation (RT) resistance. To better understand resistance mechanisms, we examined global kinase activity (kinomic profiling) in both treatment sensitive and resistant human GBM patient-derived xenografts (PDX or “xenolines”).
Anderson, Joshua C.; Duarte, Christine W.; Welaya, Karim; Rohrbach, Timothy; Bredel, Markus; Yang, Eddy S.; Choradia, Nirmal; Thottassery, Jaideep V.; Gillespie, G. Yancey; Bonner, James A.; and Willey, Christopher D., "Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines" (2014). Richard Bland Faculty Works. 12.