Date Thesis Awarded
5-2020
Access Type
Honors Thesis -- Access Restricted On-Campus Only
Degree Name
Bachelors of Science (BS)
Department
Interdisciplinary Studies
Advisor
Joshua Puzey
Committee Members
Greg Conradi Smith
Junping Shi
Lizabeth Allison
Abstract
Hybridization between species, by introducing dramatic trait variation into the population and creating viable, transgressive offsprings with novel phenotypes, can have huge evolutionary implications. Some hybrid traits have been studied in the classical genetics or population genetics context, but most complex traits are determined by multiple causes, e.g. the number of loci involved, the rewiring of the genetic circuitries, and the changes in gene expression pattern. Using the hybrid monkeyflower petal pigment patterning as an example, we present a case study to investigate complex hybrid traits in a systematic manner that includes empirical data analysis and quantitative mathematical modeling of the petal spot patterning trait in the F2 population. We identified candidate loci for a potential Turing-like dynamics that regulate the trait and simulated a 2-D F2 trait space with hybrid genetics assumptions that determine the pattern variations. Our study provides a fresh angle to study complex hybrid traits, and the workflow can be applied to other similar systems.
Recommended Citation
Zheng, Xingyu, "Modeling Hybrid Novel Traits: A case study in complex petal pigment patterning in hybrid Mimulus" (2020). Undergraduate Honors Theses. William & Mary. Paper 1492.
https://scholarworks.wm.edu/honorstheses/1492
Creative Commons License
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Comments
The combination of PDFs has disrupted the hyperlinks. Supplemental Materials see the link:
https://drive.google.com/open?id=1J9N7NBUP0BS-Ars4nazy-QIKBHzkQLG0