Date Thesis Awarded

5-2020

Document Type

Honors Thesis

Degree Name

Bachelors of Science (BS)

Department

Interdisciplinary Studies

Advisor

Joshua Puzey

Committee Members

Greg Conradi Smith

Junping Shi

Lizabeth Allison

Abstract

Hybridization between species, by introducing dramatic trait variation into the population and creating viable, transgressive offsprings with novel phenotypes, can have huge evolutionary implications. Some hybrid traits have been studied in the classical genetics or population genetics context, but most complex traits are determined by multiple causes, e.g. the number of loci involved, the rewiring of the genetic circuitries, and the changes in gene expression pattern. Using the hybrid monkeyflower petal pigment patterning as an example, we present a case study to investigate complex hybrid traits in a systematic manner that includes empirical data analysis and quantitative mathematical modeling of the petal spot patterning trait in the F2 population. We identified candidate loci for a potential Turing-like dynamics that regulate the trait and simulated a 2-D F2 trait space with hybrid genetics assumptions that determine the pattern variations. Our study provides a fresh angle to study complex hybrid traits, and the workflow can be applied to other similar systems.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.

Comments

The combination of PDFs has disrupted the hyperlinks. Supplemental Materials see the link:

https://drive.google.com/open?id=1J9N7NBUP0BS-Ars4nazy-QIKBHzkQLG0

S1-Raw_Count.xlsx (4904 kB)

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