Date Thesis Awarded
5-2011
Access Type
Honors Thesis -- Access Restricted On-Campus Only
Degree Name
Bachelors of Science (BS)
Department
Interdisciplinary Studies
Advisor
Gregory D. Smith
Committee Members
John D. Griffin
Leah B. Shaw
Abstract
Thalamocortical relay (TC) neurons in the lateral geniculate nucleus receive both retinal and cortical input; however, the two pre-synaptic signals are filtered in significantly different ways. Using a three-compartment model of a TC cell, with distinct equations for the proximal and distal dendrites, we model the synaptic plasticity of feedback signals from the cortex (corticogeniculate facilitation) and feedforward retinal input (retinogeniculate depression). We discuss the use of model-generated cross-correlograms in lending insight into the interplay of the driving and modulating afferents.
Recommended Citation
Walch, Olivia J., "Modeling synaptic facilitation and depression in thalamocortical relay cells" (2011). Undergraduate Honors Theses. William & Mary. Paper 424.
https://scholarworks.wm.edu/honorstheses/424
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Comments
Thesis is part of Honors ETD pilot project, 2008-2013. Migrated from Dspace in 2016.