Date Thesis Awarded
5-2010
Access Type
Honors Thesis -- Access Restricted On-Campus Only
Degree Name
Bachelors of Science (BS)
Department
Chemistry
Advisor
John C. Poutsma
Committee Members
Lisa M. Landino
Gary Rice
Jianjun Paul Tian
Abstract
The goal of this experiment was to determine if trends exist in the fragmentation pat- terns of heptapeptides containing lysine and its non-protein amino acid analogs (or- nithine, daba, dapa). Previous research in the laboratory of Dr. J. C. Poutsma on pentapeptides suggested that the length of the side chain on the lysine analog played a role in peptide fragmentation pathways. This study, however, found no such connection between length of side chain and fragmentation patterns suggesting that as a peptide lengthens the flexibility of the peptide bonds outweigh the side chain length factor in determining fragmentation patterns.
Recommended Citation
Challener, Douglas William, "Investigations of the Fragmentation Spectra of Heptapeptides Containing Lysine and its Non-Protein Amino Acid Homologs" (2010). Undergraduate Honors Theses. William & Mary. Paper 684.
https://scholarworks.wm.edu/honorstheses/684
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.
Comments
Thesis is part of Honors ETD pilot project, 2008-2013. Migrated from Dspace in 2016.