Date Thesis Awarded

5-2016

Access Type

Honors Thesis -- Access Restricted On-Campus Only

Degree Name

Bachelors of Science (BS)

Department

Chemistry

Advisor

Douglas Young

Committee Members

William McNamara

Robert Hinkle

Margaret Saha

Abstract

In order to elucidate the biological processes that occur in everyday life, chemical biologists have developed technologies that allow the study of a various biological systems. Bioorthogonal chemistry is an ever-growing technology that involves performing chemical reactions with biological systems that do not rely on existing biological chemistries. In this work we attempt to develop and characterize novel bioorthognal chemistries that further expand the utility of this field. Additionally, we explore the utility of fluorescent probes in labeling applications. Finally, we attempt to create novel methods of control for a gene-editing protein using light as a mechanism of regulation.

Recommended Citation

Jacobs, Taylor Harrison, "Investigation of Unnatural Amino Acids as a Means to Modulate Protein Function" (2016). Undergraduate Honors Theses. William & Mary. Paper 921.
https://scholarworks.wm.edu/honorstheses/921