Document Type
Article
Department/Program
Virginia Institute of Marine Science
Publication Date
12-2007
Journal
Comp Biochem Physiol Part D Genomics Proteomics.
Volume
2
Issue
4
First Page
257
Last Page
286
Abstract
A strong foundation of basic and applied research documents that the estuarine fish Fundulus heteroclitus and related species are unique laboratory and field models for understanding how individuals and populations interact with their environment. In this paper we summarize an extensive body of work examining the adaptive responses of Fundulus species to environmental conditions, and describe how this research has contributed importantly to our understanding of physiology, gene regulation, toxicology, and ecological and evolutionary genetics of teleosts and other vertebrates. These explorations have reached a critical juncture at which advancement is hindered by the lack of genomic resources for these species. We suggest that a more complete genomics toolbox for F. heteroclitus and related species will permit researchers to exploit the power of this model organism to rapidly advance our understanding of fundamental biological and pathological mechanisms among vertebrates, as well as ecological strategies and evolutionary processes common to all living organisms.
Keywords
Fundulus heteroclitus; ecological genomics; environmental genomics; evolutionary genomics; physiological genomics; toxicogenomics
Publication Statement
Published in final edited form as: Comp Biochem Physiol Part D Genomics Proteomics. 2007 December ; 2(4): 257–286.
Recommended Citation
Burnett, Karen G.; Bain, Lisa J.; Baldwin, William S.; (…); Van Veld, Peter A.; and Vogelbein, Wolfgang K., Fundulus as the Premier Teleost Model in Environmental Biology: Opportunities for New Insights Using Genomics (2007). Comp Biochem Physiol Part D Genomics Proteomics., 2(4), 257-286.
