Date Thesis Awarded


Access Type

Honors Thesis -- Access Restricted On-Campus Only

Degree Name

Bachelors of Science (BS)




Robert J. Hinkle

Committee Members

David W. Thompson

Lisa M. Landino

Matthew J. Wawersik


BiBr3 and Bi(OTf)3 have proven to be effective catalysts for Mukaiyama aldol reactions and Intramolecular silyl-Modified Sakurai (ISMS)/silyl-Prins type reactions towards cis-2,6-disubstituted-3,4-dihydropyrans. Herein are described studies towards the use of these Bi(III) salts in multi-component reactions to afford cyclic ethers, a structural motif found in natural products, such as the diospongins, which have been reported to posses potential therapeutic value. These investigations have also attempted to shed light on the ambiguity surrounding the method of action behind Bi(III) salts' catalytic power.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.


Thesis is part of Honors ETD pilot project, 2008-2013. Migrated from Dspace in 2016.

On-Campus Access Only